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Administration
May be taken with or without food.
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Contraindications
Hypersensitivity, anuria, aortic stenosis, outflow obstruction, hepatic cirrhosis.
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Special Precautions
Renal impairment, anaesthesia, concomitant K supplements and K - sparing diuretics, hypovolemic patients pregnancy, lactation.
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Adverse Reactions
Syncope, chest pain, abdominal pain, orthostatic hypotension, palpitation, tachycardia, GI symptoms, insomnia, nervousness, paresthesia, vertigo, skin rash, dyspnoea, gout, arthralgia, tinnitus, decreased libido, cough.
Potentially Fatal: NA. |
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Drug Interactions
Significant increase in serum K levels with K supplements and K sparing diuretics. Lithium toxicity in patients receiving lithium concomitantly. Alcohol, barbiturates, narcotics potentiate orthostatic hypotension. Dosage adjustment of antidiabetic drugs needed. Potentiation of action of other antihypertensives, corticosteroids, ACTH.
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CIMS Class
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ATC Classification
C03AA03 - hydrochlorothiazide ; Belongs to the class of low-ceiling thiazide diuretics.
C09AA02 - enalapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease. |
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